منابع مشابه
Central H2 histaminergic and alpha-2 adrenergic receptors involvement in crocetin-induced antinociception in orofacial formalin pain in rats
Previous findings have shown that saffron (Crocus sativus L.) extract and its active constituents produce antinociceptive effects in the rat models of orofacial pain. In the present study, the central H2 histaminergic and alpha-2 adrenergic receptors involvement in crocetin-induced antinociception in orofacial formalin pain in rats was evaluated.The guide cannula was implant...
متن کاملTranscriptional regulation of alpha-1 adrenergic receptors.
Regulation of alpha1-adrenergic receptors (alpha1ARs) is a rapidly expanding field of study due to the involvement of these receptors in several human diseases. For example, upregulation of alpha1bAR mRNA/protein with agonist exposure has been implicated in myocardial hypertrophy. In order to understand mechanisms underlying these findings, initial studies of human alpha1bAR transcription have ...
متن کاملRegulation of alpha and beta adrenergic receptors in man.
The sympathetic nervous system is an important regulator of the functional activities of organs such as the heart and peripheral vasculature, and also plays a vital role in modulating responses to stress. The ultimate effects of sympathetic stimulation are mediated by release of noradrenaline (norepinephrine) from nerve terminals which serves to activate the adrenergic receptors at post-synapti...
متن کاملAlterations in alpha adrenergic receptors in human cerebral arteries after subarachnoid hemorrhage.
The nature of alpha adrenergic receptors in human cerebral arteries was characterized and alteration of these receptors after subarachnoid hemorrhage (SAH) was examined using a radioligand binding assay. The specific 3H-prazosin binding to human cerebral arteries was saturable and of high affinity (KD = 4.1 nM) with a Bmax of 92 fmol/mg protein. Specific 3H-yohimbine binding to these tissues wa...
متن کاملAdrenergic Receptors in Human Atherosclerotic Coronary Arteries
Background—Adrenergic regulation of coronary vasomotion is balanced between 1-adrenergic–mediated ( 1-AR) constriction and 2-adrenergic–mediated ( 2-AR) relaxation. This study aimed at assessing the role of 2-ARs in normal, mildly atherosclerotic, and stenotic human coronary arteries. Methods and Results—During intracoronary (IC) infusion of increasing doses of the 2-AR agonist salbutamol (0.15...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1986
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)59502-6